In a groundbreaking move, Superdrug has become the first UK high street retailer to offer DoxyPEP (doxycycline post-exposure prophylaxis) through its Superdrug Online Doctor service. This preventative antibiotic, introduced in the UK in 2026, is designed to help prevent certain bacterial sexually transmitted infections (STIs) including chlamydiasyphilis and in some cases, gonorrhoea.
The initiative comes at a crucial time, as STI rates have been surging in recent years. In 2026 alone, 334,000 people were diagnosed with infections such as chlamydia, gonorrhoea, and syphilis. This rise is attributed to changing sexual behaviours and treatment resistance, making preventive measures more important than ever.
The science behind DoxyPEP
DoxyPEP is not to be confused with PrEP (pre-exposure prophylaxis), which is taken before sex to prevent HIV. Unlike PrEP, DoxyPEP is taken after sex. Timing is crucial. While DoxyPEP can be taken up to three days after sex, taking it as soon as possible within that window is generally recommended.
Research has shown that DoxyPEP can reduce the risk of chlamydia and syphilis by around 70% in men who have sex with men. Studies have also reported an average monthly decrease of 6.7% in reported cases. However, it’s important to note that DoxyPEP is not intended for the general population. It’s designed for groups who are known to be at increased risk of bacterial STIs.
Who can benefit from DoxyPEP?
Dr. Babak Ashrafi, a GP at Superdrug Online Doctor, emphasizes that DoxyPEP is another evidence-based option that can help reduce the risk of certain bacterial STIs before they occur. However, it’s not a one-size-fits-all solution. Every patient must complete a clinical assessment before treatment is prescribed.
Dr. Ashrafi advises regular STI testing, as DoxyPEP does not protect against all STIs and should be used alongside other safer-sex measures, such as using condoms. The service is offered to men who have sex with men, transgender women, sex workers, individuals who have contracted a bacterial STI in the previous year, and those who report higher-risk sexual behaviours.
How to access DoxyPEP from Superdrug
To access DoxyPEP through Superdrug Online Doctor, patients must complete an online consultation, which is reviewed by a clinician before treatment is prescribed. The pricing is as follows:
- Two tablets – £10.99
- Four tablets – £14.99
- 20 tablets – £19.99
DoxyPEP is also available in the UK from NHS sexual health clinics. This initiative by Superdrug is a significant step forward in making preventive sexual health measures more accessible to the public.
